Saturday 15 June 2013

GABAPENTIN or NEURONTIN LINK AND INFORMATION

Here is a link and some quotes from the website for Gabapentin, or known by its brand name of Neurontin in my case here in the UK.


"These are just some of the off-label uses of Neurontin we’re aware of. Let’s start with some that it’s actually good for:
"
No idea bout the Anxiety in all honesty and first I heard about it.

"The main problems with Neurontin are dizziness, cloudy thinking, fatigue and klutziness." Ooh yeah!

"Edema. Really goofy thinking - hence the nickname “Morontin.” LMAO!! FUNNY! Ooh YEAH!! LOL.

"Neurontin (gabapentin) is a prime example of the Law of Diminishing Returns in that the more you take the less you get. Seriously. It’s right there in the PI sheet / PDR" Did NOT want to read this part!!

"Hah! That’s like asking the half-life of Lamictal or the taxonomy of the Leratiomyces ceres. While the Mechanism of Action/Pharmacodynamics section of the PI sheet for every drug on the planet is predicated with some variant of “We have no freaking clue of how it works. We’re pretty sure what it doesn’t do. So our best guess is…” Parke-Davis doesn’t even bother with the guesswork. "

LMAO!!

"Gabapentin is structurally related to the neurotransmitter GABA (gamma-aminobutyric acid) but it does not modify GABAA or GABAB radioligand binding, it is not converted metabolically into GABA or a GABA agonist, and it is not an inhibitor of GABA uptake or degradation.
In vitro studies with radiolabeled gabapentin have revealed a gabapentin binding site in areas of rat brain including neocortex and hippocampus. A high-affinity binding protein in animal brain tissue has been identified as an auxiliary subunit of voltage-activated calcium channels. However, functional correlates of gabapentin binding, if any, remain to be elucidated.Neurontin PI sheet"

DO not ask me what the PI in PI Sheet stands for, Product Information or Pill Information at a  wild guess?!

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